The Orphanage was a primary setting for the episode "Tooth Fairy". It is an orphanage somewhere in the city of London, England.
History
For an unspecified time before the events of "Tooth Fairy", the Orphanage was used as a base of operations for Mrs. Wisp and the Bactus in order to steal teeth from orphans during their sleep.
A few weeks prior to the events of "Tooth Fairy", Dr. Phineas Blackpulp deduced the missing teeth phenomenon to be the work of the Bactus and has been trying to get within their walls to save the children ever sense.